Glibenclamide (Glyburide)
Glibenclamide (also known as Glyburide) is a sulfonylurea-class active pharmaceutical ingredient widely used for the management of type 2 diabetes mellitus. By stimulating insulin secretion from pancreatic beta cells and improving peripheral glucose uptake, Glibenclamide helps lower blood glucose levels and maintain glycemic control. Its well-established efficacy and safety profile make it a cornerstone therapy in oral antidiabetic treatment. Pharmaceutical companies formulate Glibenclamide into oral tablets, offering convenient dosing for patients requiring consistent glucose management.
Common Glibenclamide/Glyburide Uses and Treated Conditions
- Type 2 Diabetes Mellitus – Helps control blood glucose levels and reduce hyperglycemia.
- Adjunct to Lifestyle Therapy – Used alongside diet and exercise to improve glycemic management.
- Combination Therapy – Often combined with other oral antidiabetics for enhanced glucose control.
- Chronic Diabetes Management – Supports long-term glycemic regulation in adult patients.
Why Choose Cambrex as Your Generic API Manufacturer?
As a leading generic API supplier, Cambrex manufactures Glibenclamide API in cGMP-compliant facilities, ensuring every batch meets stringent global quality and regulatory standards. Our technical expertise, robust quality systems, and proven regulatory track record empower clients to accelerate development timelines and achieve successful market approvals. We prioritize transparency, reliability, and scientific rigor at every stage of the supply chain making us your trusted generic API manufacturer.
For detailed chemical information on Glibenclamide, visit the official CAS website.
If you’d like more information or to request a sample, contact our Generic API team today.

Cambrex your API partner
Cambrex are a leading global supplier of generic APIs. From our sites in Italy, Sweden, and the USA, we work with generic drug companies well in advance of drug patent expiration, using high quality, non-patent-infringing processes to manufacture APIs.
Contact us