Buprenorphine HCl

Buprenorphine HCl (Hydrochloride) is a semi-synthetic opioid active pharmaceutical ingredient widely used for pain management and opioid dependence treatment. As a partial agonist at the mu-opioid receptor and antagonist at the kappa-opioid receptor, Buprenorphine provides effective analgesia and reduces opioid cravings with a lower risk of respiratory depression compared to full opioid agonists. Its pharmacological profile makes it valuable in both acute and chronic pain management as well as medication-assisted treatment (MAT) for opioid use disorder. Pharmaceutical companies formulate Buprenorphine HCl into sublingual tablets, buccal films, and injectable solutions, offering flexible therapeutic options across a range of clinical settings.

Common Buprenorphine Uses and Treated Conditions

• Pain Management – Provides analgesia for moderate to severe acute and chronic pain.
• Opioid Dependence Treatment – Used in medication-assisted treatment (MAT) to reduce withdrawal symptoms and cravings.
• Combination Therapy – Often formulated with naloxone to reduce misuse potential while maintaining therapeutic benefit.
• Maintenance Therapy – Supports long-term treatment of patients with opioid use disorder.

Why Choose Cambrex as Your Generic API Manufacturer?

As a leading generic API supplier, Cambrex manufactures Buprenorphine HCl API in cGMP-compliant facilities, ensuring every batch meets stringent global quality and regulatory standards. Our technical expertise, robust quality systems, and proven regulatory track record empower clients to accelerate development timelines and achieve successful market approvals. We prioritize transparency, reliability, and scientific rigor at every stage of the supply chain making us your trusted generic API manufacturer.

For detailed chemical information on Buprenorphine HCl, visit the official CAS webpage.

If you’d like more information or to request a sample, contact our Generic API team today.