Brotizolam
Brotizolam is a thienodiazepine-class active pharmaceutical ingredient widely used as a short-acting hypnotic for the treatment of insomnia and related sleep disturbances. By enhancing the effect of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the central nervous system, Brotizolam induces sedative, hypnotic, and anxiolytic effects. Its rapid onset and relatively short half-life make it particularly suited for patients experiencing difficulty with sleep initiation or nocturnal awakenings. Pharmaceutical companies formulate Brotizolam into oral tablets, providing effective and well-tolerated therapy for sleep disorders.
Common Brotizolam Uses and Treated Conditions
- Insomnia – Improves sleep onset and sleep maintenance.
- Sleep Disturbances – Addresses nocturnal awakenings and poor sleep quality.
- Anxiety-Related Sleep Disorders – Provides sedation and anxiolytic effects in patients with sleep disruption.
- Short-Term Hypnotic Therapy – Used for the short-term management of transient or situational insomnia.
Why Choose Cambrex as Your Generic API Manufacturer?
As a leading generic API supplier, Cambrex manufactures Brotizolam API in cGMP-compliant facilities, ensuring every batch meets stringent global quality and regulatory standards. Our technical expertise, robust quality systems, and proven regulatory track record empower clients to accelerate development timelines and achieve successful market approvals. We prioritize transparency, reliability, and scientific rigor at every stage of the supply chain making us your trusted generic API manufacturer.
For detailed chemical information on Brotizolam, visit the official CAS webpage.
If you’d like more information or to request a sample, contact our Generic API team today.

Cambrex your API partner
Cambrex are a leading global supplier of generic APIs. From our sites in Italy, Sweden, and the USA, we work with generic drug companies well in advance of drug patent expiration, using high quality, non-patent-infringing processes to manufacture APIs.
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