IND submission is a major milestone in the life of your drug. We can provide all supporting analytical data to help ensure a smooth application process.
We have the expertise, flexibility, and resources to provide a full range of pharmaceutical API custom development services at every stage of the lifecycle.
We can provide lab-, kilo- and pilot-scale manufacturing for preclinical studies and all phases of clinical trials, supplying milligram to kilogram quantities.
Cambrex brings more than 40 years of generic API manufacturing experience to its pharmaceutical partners. From our sites in Italy, Sweden, and the USA, we are a leading global supplier of generic APIs.
Drug substance tech transfer sounds so simple on the surface, but it’s a complex activity carrying a number of technical, regulatory, and quality risks.
At Snapdragon Chemistry, now part of Cambrex, our chemists specialize in creating custom solutions and technologies to take on your toughest process development and production challenges. This includes expertise in designing and building reactors that enable seamless technology transfer as a process scales up for commercial manufacturing.
At Cambrex, we provide a range of technologies equipped to solve your API manufacturing challenges, and we are flexible enough to handle the most complex molecules.
If you’re looking to outsource drug product development to a CDMO, you need a collaborative partner who will engage you deeply to understand the unique needs of your project.
From pre-formulation to commercial manufacturing and packaging, you can trust Cambrex to deliver your complex dosage forms with the perfect combination of technology, expertise, and collaboration.
We are equipped to take on projects at any size or scale, offering established pediatric formulation and development expertise and to-scale manufacturing capabilities.
Biopharma companies at all stages of development, rely on our expertise and broad capabilities to produce the clinical trial supply of drug products they need, when they need them.
You can rely on our extensive portfolio of analytical development solutions and testing services to rapidly advance your molecule for the greatest chance of success.
Cambrex offers a comprehensive suite of testing services for complex biopharmaceuticals including standalone analytical R&D, method validation, release testing, ICH stability, and routine QC testing.
We’re solid state chemistry experts who can deliver timely, phase-appropriate solutions to optimize the physical stability of your API, develop a more bioavailable formulation or overcome other challenges.
Cambrex’s experienced analysts are well-equipped to ensure microbial testing is of the highest quality for our customers and delivered with a quick and reliable turnaround.
Cambrex and Q1 Scientific’s stability storage and sample management capabilities provide a variety of pharmaceutical storage conditions, with walk-in and reach-in chambers that meet all ICH Q1A requirements.
Cambrex is here to support you in early-phase development. Our development experts apply their ingenuity and skill to address your unique challenges.
Our teams of creative problem-solvers work closely with you to accelerate drug development timelines, optimize processes, and meet regulatory requirements.
We understand that the commercial phase of drug development can be challenging, especially when it comes to manufacturing at scale and meeting changing market demands.
Cambrex is a leading global supplier of more than 70 generic APIs, as well as intermediates and derivatives.
As leaders in the industry, we understand that traditional photoreactors used in batch processing can’t achieve the same throughput as continuous flow reactors, so we decided to design and build our own specifically for flow chemistry.
Introducing the IRIS LAB™ and IRIS MAX™ Photoreactors from Snapdragon Chemistry — a technology platform that combines scalability with flexibility. Incorporate IRIS reactors in your own labs or leverage the systems in one of Cambrex’s global sites. Our recent 12,000 square foot expansion in Waltham, Massachusetts increases our ability to implement these reactors in-house with additional kilo-lab operations designed for multistep, end-to-end continuous processing.
Either way — in your facility or ours — you will have an end-to-end solution to increase your agility as you manage your ever-changing landscape of products while meeting necessary business requirements.
Download our IRIS LAB data sheet and learn more about the systems below.
Looking for a partner that balances passion with painstaking attention to detail? Speak to one of our Snapdragon experts about how we can help you succeed.
The IRIS LAB Photoreactor is a high-yield, small-footprint photoreactor suitable for laboratory development and proof-of-concept (PoC) material delivery (up to 10 g/h productivity). It uses LEDs to produce high-intensity photons — and a wide range of photoreaction temperatures, which can be controlled precisely with cooling ports connected to chillers. This minimizes thermal fatigue on individual components and on the entire system, extending the lifetime of the product.
Processes developed in IRIS LAB are directly scalable for kilogram delivery in IRIS MAX photoreactor.
The IRIS MAX Photoreactor extends the capabilities of the IRIS LAB system by supporting kilo lab operation in a fume hood. Processes can be seamlessly scaled up from the IRIS LAB to IRIS MAX with consistently high productivity, using the same LEDs. Scale-up is achieved by adding banks of 5 kW LEDs, up to 10 lamps (~100 mL each with 0.1875″ outer diameter and 0.125″ inner diameter tubing).
Our recent expansion in Waltham, Massachusetts, expands our ability to implement these reactors in-house with additional kilo lab operations. With an added 12,000 square feet, Snapdragon now offers process research and development suites with 24 hoods, a GMP stability suite, and a fifth GMP kilo lab, designed for multistep, end-to-end continuous processing.
In this article, Cambrex’s Chief Scientific Officer and President of Snapdragon Chemistry, Matthew Bio, sat down with CPHI for an interview to talk about the project that won Snapdragon the 2023 CPHI Pharma Award for API Development.
Cambrex offers continuous flow process development services to provide our customers with improved control, increased safety, lower costs, and more.
During this webinar, we showcase how Snapdragon’s CM lab development platform accurately models production-scale systems enabling right-first-time scale-up.