IND submission is a major milestone in the life of your drug. We can provide all supporting analytical data to help ensure a smooth application process.
We have the expertise, flexibility, and resources to provide a full range of pharmaceutical API custom development services at every stage of the lifecycle.
We can provide lab-, kilo- and pilot-scale manufacturing for preclinical studies and all phases of clinical trials, supplying milligram to kilogram quantities.
Cambrex brings more than 40 years of generic API manufacturing experience to its pharmaceutical partners. From our sites in Italy, Sweden, and the USA, we are a leading global supplier of generic APIs.
Cambrex offers cutting-edge capabilities in peptide development and manufacturing, combining innovative technologies, diverse applications and specialized expertise to meet the growing demand for peptide-based therapeutics.
Drug substance tech transfer sounds so simple on the surface, but it’s a complex activity carrying a number of technical, regulatory, and quality risks. Cambrex specializes in seamless technology transfers and quick onboarding to keep your program on track.
At Cambrex, we provide a range of technologies equipped to solve your API manufacturing challenges, and we are flexible enough to handle the most complex molecules.
At Snapdragon Chemistry, now part of Cambrex, our chemists specialize in creating custom solutions and technologies to take on your toughest process development and production challenges. This includes expertise in designing and building reactors that enable seamless technology transfer as a process scales up for commercial manufacturing.
You can rely on our extensive portfolio of analytical development solutions and testing services to rapidly advance your molecule for the greatest chance of success.
Cambrex’s experienced analysts are well-equipped to ensure microbial testing is of the highest quality for our customers and delivered with a quick and reliable turnaround.
We’re solid state chemistry experts who can deliver timely, phase-appropriate solutions to optimize the physical stability of your API, develop a more bioavailable formulation or overcome other challenges.
Cambrex and Q1 Scientific’s stability storage and sample management capabilities provide a variety of pharmaceutical storage conditions, with walk-in and reach-in chambers that meet all ICH Q1A requirements.
Cambrex offers extensive development services tailored to meet your drug product needs in early development. From pre-formulation to Phase II, we ensure your products are developed with speed, flexibility, and quality in mind.
Whether you need rapid development, flexible manufacturing solutions, or high-quality production, Cambrex is your trusted partner for advancing your drug product from concept to the clinic.
Cambrex is here to support you in early-phase development. Our development experts apply their ingenuity and skill to address your unique challenges.
Our teams of creative problem-solvers work closely with you to accelerate drug development timelines, optimize processes, and meet regulatory requirements.
We understand that the commercial phase of drug development can be challenging, especially when it comes to manufacturing at scale and meeting changing market demands.
Cambrex is a leading global supplier of more than 70 generic APIs, as well as intermediates and derivatives.
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The formation of Csp3–Csp2 bonds is a powerful means of synthesizing high-value chemicals. Nickel catalysis has offered numerous avenues to Csp3–Csp2 bond assembly via cross coupling of Csp3 electrophiles, but…
The translation of olefin metathesis reactions from the laboratory to process scale has, historically, been challenging with traditional batch techniques due to mass-transport limitations that negatively influence the efficiency of…
Complex [(DMPU)2Zn(CF2H)2] 1 is a crystalline organometallic reagent with utility in various catalytic difluoromethylation reactions under mild conditions. Unfortunately, this reagent isn’t commercially available, and the procedure for the preparation…
This article shares our process for developing an improved API synthesis of raltegravir. Through this process, the team isolated a new process intermediate and develop conditions to solve the selectivity…
In this article, we discuss how our team at Snapdragon Chemistry, in collaboration with Qpex Biopharma, Inc., designed and built a convenient development-scale reactor (0.44 mol/h) to prepare diazomethane from…
Leveraging a High-Temperature Thermal Racemization to Recycle the Classical Resolution Waste Stream In part one of this two-part series, “Development of a Classical Resolution to Prepare an Atropisomerically Pure Sotorasib…
In this article, we describe our work with Amgen on the process development efforts to improve the final methylation step in the AMG 397 drug substance process, culminating in the…
In our recent article, our team in Milan explains how they developed an improved synthesis of the active pharmaceutical ingredient (API) dimethyl fumarate. Previously, commercial production strategies of dimethyl fumarate…
The ketone intermediate, LSN647712, is a key synthetic intermediate for Eli Lilly’s drug substance lasmiditan during its manufacturing process. In this article, we explain how our team at Snapdragon Chemistry…
In a recent article in Chemistry Today, Snapdragon Chemistry’s David Ford discusses how AI and data science may fundamentally change how we approach process development and early deliveries of active…