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Scientist II – Biopharma


Durham, NC, USA


Analytical Support

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At Cambrex, it’s our people that set us apart. We work locally and have an impact globally. We’re committed to attracting, nurturing and retaining a passionate and talented team of experts in our fast paced and growing company. You will be valued and recognized. We offer an exceptional benefits package including medical, dental, vision, Life, STD, LTD, generous vacation in your first year, sick time, and retirement savings!

Cambrex is the small molecule company that provides drug substance, drug product and analytical services across the entire drug lifecycle. Known for our scientific and manufacturing excellence and customer focus, we offer a range of career opportunities across our global network of locations. As a team, we share one goal – to improve the quality of life for our customers’ patients across the world.


Develop biopharmaceutical assays, bioassays, and validate the methods for GMP use


  • Techniques include but are not limited to: qPCR (residual DNA, copy number), virus titer by plaque assay (mammalian and bacterial based), ELISAs, Endotoxin, total DNA, total RNA, HPLC-(QQQ, UV, CAD, ELSD, RI, FLD, MS), SDS PAGE, Western blots, HIAC and NS300 particle counting, Next Generation Sequencing (NGS) library preparation workflows, and more
  • May assist DMPK-ADME (Tox) group in HPLC-QQQ testing and conduct similar tests on complex biopharmaceutical products
  • Cell culture, viral plaque assays, and other bio-assays (xCelligence)
  • Assist in writing new SOPs, implementing efficient and effective workflows, and onboarding new methods and instruments in a growing group in a fast-paced work environment.
  • May spend 60-80% of time in the lab and 40-20% writing methods, reports, protocols, and SOPs
  • ICH validation and stability testing for a variety of molecularly diverse biomolecules and viral active pharmaceutical ingredients
  • Execution of analytical testing as per approved protocols, current Pharmacopoeia, and test methods etc.
  • Work effectively in a team environment to grow capabilities and add value to the customer
  • Draft and release certificates of analyses, reports, protocols, and methods per cGMP and ICH practices
  • May interact with clients to report on method development activities/results
  • Assist sample management in receiving biological materials and manage samples in LIMS


  • PhD or master’s degree in cell biology, molecular biology, biochemistry, or equivalent
  • Minimum:  0-3 years of experience (PhD) or 2+ years (Masters) in GMP Analytical Testing environment or similar
  • ELISA, cell culture, plate-based assays, qPCR, and other molecular biology techniques are desired
  • Understanding of applicable GMP/ICH requirements is desirable
  • Preference to those that demonstrate a winning attitude, drive, great organizational skills, and attention to detail
  • Passionate about technical expertise and quality work while remaining an inclusive team member
  • Flexible mindset to be able to learn and troubleshoot new techniques
  • Must be able to schedule time and be organized
  • Must have strong operational knowledge of molecular biology and/or cell culture techniques
  • Use of a variety of biopharmaceutical instrument software including: SoftMax Pro (Plate reader), Quant Studio 5 (qPCR), MiSeq (NGS), Image Lab Secure (Bio-RAD ChemiDoc MP), Empower, Mass Hunter
  • Ability to handle multiple priorities and projects concurrently
  • Demonstrated accountability with prior positions
  • Ability to adhere to a strict attendance policy
  • Excellent verbal and written communication and analytical skill with a strong attention to detail

Preferred Qualifications:

  • 2+ years of cGMP biopharmaceutical method development and QC testing with ability to technically lead projects
  • Experience with SoftMax Pro (Plate reader), Quant Studio 5 (qPCR), Image Lab Secure (Bio-RAD ChemiDoc MP), Empower, Mass Hunter, Next Generation Sequencing (NGS) workflows
  • Experience with DMPK-ADME bioanalytical techniques: HPLC-MSMS
  • Prospective analysts should demonstrate the following important “soft” skills
    • Attention to detail
    • Strong Communication skills
    • Ability to prioritize and work efficiently
    • Customer focus
    • Driven (we prefer to foster growth and promote internally)
    • Ability to troubleshoot and develop a variety of methods intended for GMP use
    • Friendly team attitude