Cambrex is a leading global supplier of Active Pharmaceutical Ingredients (APIs) and services to the generic pharmaceutical industry. We have long-standing expertise in the development, process optimization, scale-up and cGMP production of more than 70 APIs. Equally important, we are familiar with European and U.S. Intellectual Property Rights and all our processes are carefully checked to avoid patent infringement. The experience of our R&D scientists, the competence of our chemists and the flexibility of our cGMP facilities guarantee to our customers´ products with characteristics of a global quality.

We have a Raw Material and Intermediates Warehouse and a cGMP active pharmaceutical ingredient (API) finishing facility. The combination of our R&D laboratories, enhanced warehouse, and cGMP facility will ensure that we will continue to be a leading generic active pharmaceutical ingredients manufacturer.

Our capabilities include synthesis route selection with respect for patents, laboratory process validation, optimization and verification of the prospects for successful scale-up from bench to commercial quantities. Pilot facilities are available at various locations to satisfy production of experimental quantities from kilo to hundreds of kilograms. Production is performed in multipurpose plants with a total capacity of 380 m³. The final steps of manufacture, like purification, drying and milling, are handled in separate departments and often customized for the most demanding customer needs.

We operate in adherence to stringent FDA cGMP standards and other regulatory requirements.  We are committed to satisfying the requirements of the generic pharmaceutical industry quickly and efficiently. We value the relationships we have established with our customers worldwide and we will continue to meet the needs of the pharmaceutical producers.

Cambrex currently has an offering of over 70 APIs and intermediates, which are manufactured in our Charles City Iowa and Milan facilities:

*    under advanced development
**  under development
This list is not to be construed as a representation of non-infringement or as an offer to sell in those countries where such would constitute an infringement of third parties’ patent rights.

Intermediates	CAS Number
Chloronitrobenzoic acids and derivatives
3-Amino-4-chlorobenzoic acid (4,3-CABA)	2840-28-0
2-Chloro-5-aminobenzoic acid (2,5-CABA)	89-54-3
2-Chloro-4-nitrobenzoic acid (2,4-CNBA)	99-60-5
4-Chloro-2-nitrobenzoic acid (4,2-CNBA)	6280-88-2
4-Chloro-3-nitrobenzoic acid (4,3-CNBA)	96-99-1
2-Chloro-5-nitrobenzoic acid (2,5-CNBA)	2516-96-3
Dinitrobenzoic acids and derivatives
3,5-Dinitrobenzoic acid (3,5-DNBA) 99-34-3
Nitrobenzoic acids and derivatives
4-Aminobenzoic acid (PABA)	150-13-0
4-Aminobenzoic acid ethyl ester (Benzocaine Tech)	94-09-7
3-Nitrobenzoic acid (MNBA)	121-92-6
Sodium meta-nitrobenzoate	827-95-2
Nitrophthalic acids and derivatives
5-Nitroisophthalic acid (5-NIPA)	618-88-2
5-Nitroisophthalic acid dimethyl ester (5-NIPA-DME)	13290-96-5
Pyridine derivatives
Isocinchomeronic acid (ICA)	100-26-5
Picolinic acid	98-98-6
Miscellaneous
Mucic acid (Galactaric acid)	526-99-8
2-Phenylbenzimidazole (2PB)	716-79-0
Sodium p-sulfophenyl methallyl ether (SPME)	1208-67-9
Sodium p-phenolsulfonate (Tech & Refi ned)	825-90-1