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Cambrex Drug Delivery Technology

Cambrex offers its customers a novel yet simple way to control critical aspects of its drug products. The Cambrex Camouflage polymer resin-based drug delivery platform provides improved drug stability, controlled release and taste masking as its major benefits.

Camouflage Drug Delivery Technology launched based on its ability to mask the taste of bitter drugs. Through the use of an insoluble, tasteless polymeric resin, Cambrex has assisted drug companies in the commercialization of a number of important oral thin film (OTF) and orally dissolving tablet (ODT)-based drug products. By changing the organoleptic properties of the active pharmaceutical ingredient itself, the polymer resin makes the drug imperceptible to the consumer and thus “Camouflages” the taste of the drug.

Taste masking is becoming a more important property that must be considered in formulation of  drug products largely because of the changing patient demographics and the trend. around self medication. Drug products are no longer just swallowed in tablet form. Today they are chewed or dissolve in the oral cavity and this increased residence time has led to changes in the look and taste of drug products.

Cambrex attained its first major success with its Camouflage Drug Delivery Technology and the introduction of Nicotine Polacrilex (NPR), the most widely used form of Nicotine for orally administered drugs used in Nicotine Replacement Therapy (NRT) or Smoking Cessation. Cambrex is the leader in NPR technology and has a global presence in this market.

  Nicotine Polacrilex

The Camouflage technology from Cambrex offers the pharmaceutical formulator more than just taste masking benefits. This resin-based technology can control drug release and improve the stability of the drug product’s active ingredient. Working with customers, our development personnel design and test the make up of the drug product intermediate (drug + Camouflage resin) to ensure the optimization of the drug’s efficacy.

Immediate release Modified Release

 

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