Enzymatic transformations are known for high efficiency on the molecular level, particularly when it comes to specificity and chiral purity. However, when it comes to production of large commercial quantities there are many limitations. The enzymes are often active in only small pH and temperature ranges, often only in water based systems, and are often inactivated during the reaction. Moreover, they normally work only in dilute solutions, and the separation of the biological material from the reaction mixture is often tedious. 

Cambrex has developed processes for cGMP production of tens of tons of chiral molecules with enzymatic technologies. The goal is to become a world-leading producer of large quantities of chiral molecules. Through highly efficient processes and plants designed for high throughput, we strive to produce chiral compounds cost effectively.